Diogenes Syndrome.

Area of Science:

• Geriatrics
• Neuropsychiatry
• Social Work

Background:

• Diogenes syndrome (DS) is a complex neurobehavioral syndrome characterized by severe domestic squalor, pathological hoarding, lack of insight, and self-neglect.
• DS can be primary, often in the elderly, or secondary to conditions like psychosis or bipolar disorder.
• Despite being known for decades, the underlying mechanisms of DS remain incompletely understood.

Purpose of the Study:

• To explore the neurocognitive underpinnings of Diogenes syndrome.
• To highlight the need for multidimensional approaches in managing DS.
• To advocate for earlier intervention and further research.

Main Methods:

• Review of existing literature on Diogenes syndrome.
• Neurocognitive analysis focusing on frontal lobe vulnerability.
• Discussion of clinical, psychiatric, neurological, social, and ethical considerations.

Main Results:

• Frontal lobe dysfunction is implicated in disrupted decision-making, leading to core symptoms of DS.
• The syndrome's transnosographic nature necessitates a holistic, multidimensional assessment and management strategy.
• Current understanding of DS mechanisms is limited, requiring further investigation.

Conclusions:

• Earlier intervention in Diogenes syndrome is essential for improved clinical knowledge and patient outcomes.
• Prospective studies, laboratory experiments, and randomized controlled trials are needed to develop effective treatments.
• Future pharmacological and non-pharmacological strategies offer hope for alleviating this socially debilitating condition.