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Updated: Feb 18, 2026
A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
Published on: July 6, 2017
Two case reports: Colorectal adenocarcinoma in children
Chang Hoon Ahn1, Soon Chul Kim
1Department of Pediatrics, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine of Chonbuk National University - Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
Rationale:
Colorectal cancer in children is rare, with delayed diagnosis and advanced stage at presentation in high mortality. Early detection of colorectal cancer is, therefore, important for better prognosis.
Patient Concerns:
Thirteen-year-old boy presented with symptoms of melena, vomiting, and abdominal pain for 6 months. 18-year-old girl was hospitalized due to the symptoms of hematochezia, and persistent abdominal pain for 6 months. They have no chronic disease or familial history of malignancy.
Diagnoses:
We encountered 2 teenagers diagnosed with colorectal cancer.
Interventions:
Both patients had the same histological findings in postoperation colonic biopsy and underwent surgical resection.
Outcomes:
The boy fully recovered with only surgery, but the girl died, despite receiving adjuvant chemotherapy for the advanced stage of cancer.
Lessons:
We recommend early and active evaluation, including a pediatric colonoscopy, in a child with suspected malignancy.
