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87Rb NMR studies of the perfused rat heart
J L Allis1, C D Snaith, A M Seymour
1Department of Biochemistry, University of Oxford, England.
FEBS Letters
|January 2, 1989
Abstract:
We have studied 87Rb+ fluxes in the perfused rat heart using nuclear magnetic resonance spectroscopy (NMR). A simple model for the interpretation of the data is presented. A comparison of radioactively measured K+ fluxes and the K+ fluxes deduced from the 87Rb+ measurements shows them to be very similar. This method provides a means of noninvasively measuring uni-directional K+ fluxes in the heart.