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Dendrimers for Ocular Drug Delivery
Michael G Lancina1, Hu Yang2,3,4
1Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, United States.
Abstract:
Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this review, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.
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