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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Renal Medullary Carcinoma is a Diagnosis Worth Considering: Case Report
Christopher Thomas1, Azhar Khan1, Hari Khrishnan1
1Department of Urology, Mayday University Hospital, Croydon, London, UK.
Abstract:
Medullary Renal Carcinoma is a rare, highly malignant neoplasm that originates in the renal medulla and typically affects young black patients with sickle cell trait. We report the case of a 17-year-old boy with a symptomatic left renal tumour. CT revealed that the mass originated from the kidney and was associated with a large para-aortic lymph node mass. Hemoglobin electrophoresis showed sickle cell trait and a needle biopsy confirmed the diagnosis of Renal Medullary Carcinoma. We discuss the obscurity and implications of such a diagnosis. It is essential that clinicians are aware of this diagnosis as any delay can be fatal in the outcome of this highly aggressive and extremely rare cancer.
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