Related Experiment Videos
Optic disc cupping: prevalence findings from the WESDR
B E Klein1, S E Moss, Y L Magli
1Department of Ophthalmology, University of Wisconsin Medical School, Madison 53792.
Investigative Ophthalmology & Visual Science
|February 1, 1989
Summary
In individuals with diabetes mellitus, optic nerve cupping is not directly linked to high intraocular pressure (IOP). However, a history of glaucoma was associated with larger cup-to-disc ratios in this diabetic population.
Area of Science:
- Ophthalmology
- Diabetology
- Optic Nerve Health
Background:
- Optic disc cupping is a key indicator of optic nerve damage due to pressure.
- Individuals with diabetes mellitus may have optic nerves more vulnerable to intraocular pressure (IOP).
Purpose of the Study:
- To investigate the relationship between intraocular pressure and optic disc cupping in people with diabetes mellitus.
- To determine if diabetes impacts the susceptibility of optic nerves to IOP-induced damage.
Main Methods:
- Utilized stereoscopic fundus photographs from the Wisconsin Epidemiologic Study of Diabetic Retinopathy.
- Measured vertical and horizontal disc and cup diameters by trained graders.
- Calculated mean cup-to-disc ratios for each eye.
Main Results:
- A history of glaucoma showed a significant association with larger cup-to-disc ratios.
- Elevated intraocular pressure (high IOP) was not found to be associated with larger cup-to-disc ratios.
- Panretinal photocoagulation treatment did not correlate with increased cup-to-disc ratios.
Conclusions:
- In diabetic patients, optic disc cupping is not directly correlated with intraocular pressure levels.
- Glaucoma history is a significant factor associated with increased optic disc cupping in diabetic individuals.
- Further research may explore other factors influencing optic nerve health in diabetes.