Vascular complications after percutaneous mitral valve repair and venous access closure using suture or closure

Birgit Steppich1, Felix Stegmüller1, Philipp Moritz Rumpf

  • 1Deutsches Herzzentrum der Technischen Universität München, München, Germany.

Insights

For patients undergoing percutaneous mitral valve repair, both suture and closure devices are safe and effective for access-site closure. Neither method showed a significant advantage in reducing vascular or bleeding complications.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Percutaneous mitral valve repair (MitraClip) is performed in high-risk patients.
  • Large access sheaths (24 Fr) necessitate effective closure techniques.
  • The impact of closure strategies on complications is not well-established.

Purpose of the Study:

  • To compare the safety and efficacy of suture versus closure devices for access-site closure after MitraClip.
  • To evaluate rates of vascular and bleeding complications associated with each closure method.

Main Methods:

  • Retrospective analysis of 277 high-risk patients undergoing MitraClip between 2009-2015.
  • Access-site closure was achieved using Z-suture (n=150) or a closure device (n=127).
  • Complications were assessed using Valve Academic Research Consortium (VARC-2) criteria, including vascular events and bleeding.

Main Results:

  • No significant difference in VARC-2 major or minor access-site complications between suture and closure device groups (2.7% vs 3.1%, P=0.81).
  • Bleeding complication rates were comparable (4.0% vs 4.0%, P=0.81).
  • Unplanned endovascular interventions were similar (2.0% vs 3.1%).

Conclusions:

  • Both Z-suture and closure devices are feasible and safe for access-site closure post-MitraClip.
  • No significant benefit of one closure strategy over the other was observed regarding VARC-2 complications.
Abstract

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