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In Reply: The Use of Vancomycin Powder for Surgical Prophylaxis Following Craniotomy

Allen L Ho1, Gordon H Li1

  • 1Department of Neurosurgery Stanford School of Medicine Stanford, California.

Neurosurgery
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PubMed
Abstract

No abstract available in PubMed .

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Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
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