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Related Experiment Videos

The effect of centrifuging bone cement.

J P Davies1, M Jasty, D O O'Connor

  • 1Orthopaedic Research Laboratories, Massachusetts General Hospital, Boston, MA 02114.

The Journal of Bone and Joint Surgery. British Volume
|January 1, 1989
PubMed
Summary

Bone cement fatigue life varied greatly, influenced more by composition than porosity. Simplex P, when chilled and centrifuged, exhibited the highest fatigue life and remained easy to use.

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Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Materials Engineering

Background:

  • Bone cements are critical in orthopedic surgery for implant fixation.
  • Understanding factors affecting bone cement performance, like fatigue life, is essential for patient outcomes.
  • Porosity and mixing conditions can influence cement properties.

Purpose of the Study:

  • To evaluate the porosity and fatigue life of five common bone cements.
  • To determine the impact of centrifugation and low-temperature mixing on bone cement properties.
  • To identify bone cement formulations with optimal fatigue resistance and handling characteristics.

Main Methods:

  • Tested five bone cements: Simplex P, LVC, Zimmer regular, CMW, and Palacos R.
  • Evaluated porosity and fatigue life under various conditions: with/without centrifugation, and at room temperature vs. 0°C monomer.

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  • Assessed cement handling properties (liquidity) after mixing.

    • Main Results:

    • Fatigue life varied by nearly 100-fold across tested specimens.
    • Fatigue life was not solely dependent on porosity but significantly influenced by cement composition.
    • Simplex P, mixed with monomer at 0°C and centrifuged for 60 seconds, demonstrated the highest fatigue life.
    • This optimal Simplex P formulation maintained sufficient liquidity for easy clinical application.

    Conclusions:

    • Bone cement composition is a primary determinant of fatigue life, outweighing porosity.
    • Specific mixing protocols (low temperature, centrifugation) can significantly enhance fatigue performance.
    • Simplex P, under optimized conditions, offers superior fatigue resistance and clinical usability, crucial for long-term implant stability.