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[Fungal keratitis]
T Bourcier1, A Sauer1, A Dory2
1Service d'ophtalmologie, Nouvel hôpital civil, EA7290, FMTS, hôpitaux universitaires, université de Strasbourg, 1, place de l'Hôpital, BP 426, 67091 Strasbourg cedex, France.
Abstract:
Fungal keratitis, or keratomycoses, are corneal infections which must be considered in cases of corneal trauma, prior corneal surgery, chronic ocular surface disease, topical corticosteroids or contact lens wear. Filamentous fungi or yeasts may be involved. Presenting clinical features such as corneal infiltrates with feathery edges and/or raised surface, intact epithelium with deep stromal involvement, satellite lesions, endothelial plaques, lack of improvement with antibiotics and worsening with steroids are suggestive of fungal keratitis. Corneal scraping for laboratory examination is mandatory. Medical management with antifungal eye drops and systemic agents should be started as soon as possible. Surgical interventions are required in a significant number of cases to control the infection. The prognosis of fungal keratitis is worse than that of bacterial keratitis.
Insights
Fungal keratitis (corneal infections) can occur after eye trauma or surgery. Early diagnosis and treatment with antifungal drops and possible surgery are crucial for a better outcome compared to bacterial infections.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Fungal keratitis, also known as keratomycoses, are serious corneal infections.
- Risk factors include corneal trauma, surgery, ocular surface disease, steroid use, and contact lens wear.
- Both filamentous fungi and yeasts can cause these infections.
Purpose of the Study:
- To outline the key clinical features suggestive of fungal keratitis.
- To emphasize the importance of prompt laboratory diagnosis and treatment.
- To discuss management strategies and compare prognosis with bacterial keratitis.
Main Methods:
- Clinical presentation analysis.
- Laboratory examination of corneal scrapings.
- Review of medical and surgical management protocols.
Main Results:
- Suggestive clinical signs include feathery infiltrates, satellite lesions, and lack of response to antibiotics.
- Corneal scraping is essential for definitive diagnosis.
- Fungal keratitis often requires prompt antifungal therapy and potentially surgery.
Conclusions:
- Fungal keratitis presents with specific clinical signs and requires urgent management.
- Prompt diagnosis via corneal scraping and initiation of antifungal treatment are critical.
- The prognosis for fungal keratitis is generally poorer than for bacterial keratitis.
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