Ketogenic diet and anorexia nervosa
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Updated: Feb 18, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
1Boston University, Department of Psychology, 64 Cummington Street, Boston, MA 02212, United States.
Abstract:
This hypothesis suggest that starvation-induced ketosis, which leads to a fundamental biochemical change in the metabolic fuel supply of the brain, is uniquely anxiolytic and rewarding to patients prone to AN. Ketosis can easily be replicated by a unique diet marked by high fat, moderate protein, and very low carbohydrate. This diet, known as a ketogenic diet (KGD) mimics starvation, thus allowing the patient to experience the anxiolytic state of ketosis, and yet avoid the morbidity of starvation.
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