Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

488
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
488
Clinical Trials: Overview01:11

Clinical Trials: Overview

5.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.1K
Clinical Trials01:16

Clinical Trials

10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Cancer Survival Analysis01:21

Cancer Survival Analysis

787
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
787

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preconception and first-trimester metformin for improving pregnancy outcomes in women with polycystic ovary syndrome.

The Cochrane database of systematic reviews·2026
Same author

Miscarriage, self-harm, and psychiatric disorders in first-time pregnant women: Evidence from a linkage study.

Social science & medicine (1982)·2026
Same author

Prevention of postpartum haemorrhage: from evidence to implementation at scale.

Lancet (London, England)·2026
Same author

Postpartum haemorrhage: epidemiology, consequences, and missed opportunities.

Lancet (London, England)·2026
Same author

Diagnosis and treatment of postpartum haemorrhage: a race against time.

Lancet (London, England)·2026
Same author

Barriers and bottlenecks to implementation of WHO recommendations for prevention, detection, and treatment of postpartum hemorrhage: a mixed-methods triangulation study.

Implementation science communications·2026
Same journal

The development of a Patient Decision Aid and Patient Concerns Inventory for people diagnosed with recurrent head and neck cancer: a mixed-methods study protocol.

BMJ open·2026
Same journal

Effect of transitioning from sterile to clean urinary catheterisation on catheter-associated urinary tract infections and sustainability: a pre-post study in a Dutch university hospital.

BMJ open·2026
Same journal

Impact of vitamin D supplementation on preterm births and premature rupture of membranes: a study protocol for a double-blind randomised controlled trial.

BMJ open·2026
Same journal

Mapping cancer literacy levels, barriers and facilitators, educational initiatives and misinformation narratives: multiple scoping review protocol.

BMJ open·2026
Same journal

Transcutaneous vagus nerve stimulation as add-on therapy versus pharmacotherapy alone (TRAVAST): study protocol for a prospective, randomised, triple-blind, controlled, multicentre trial.

BMJ open·2026
Same journal

Stewarding scarce response capacity: an inductive qualitative interview study of emergency medical dispatchers' prioritising ambulance resources.

BMJ open·2026
See all related articles

Related Experiment Video

Updated: Feb 18, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.8K

Core Outcome Sets in Miscarriage Trials (COSMisT) study: a study protocol.

Paul Smith1, Natalie Cooper2, Rima Dhillon-Smith1

  • 1Academic Department, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham Women's Hospital, Birmingham, West Midlands, UK.

BMJ Open
|November 19, 2017
PubMed
Summary
This summary is machine-generated.

This study outlines the development of Core Outcome Sets for Miscarriage Trials. These standardized outcome sets will improve research consistency and patient-centered care in miscarriage management.

Keywords:
core outcome setdelphiearly pregnancy lossmiscarriagespontaneous abortion

More Related Videos

Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma
06:24

Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma

Published on: July 6, 2022

5.5K
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

11.3K

Related Experiment Videos

Last Updated: Feb 18, 2026

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.8K
Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma
06:24

Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma

Published on: July 6, 2022

5.5K
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

11.3K

Area of Science:

  • Reproductive Health
  • Clinical Trial Methodology
  • Patient-Reported Outcomes

Background:

  • Core outcome sets standardize outcome measurement in clinical research.
  • Standardization enhances comparability and reduces bias in study findings.
  • Patient-centered outcomes are crucial for improving miscarriage care quality and cost-effectiveness.

Purpose of the Study:

  • To describe the rationale and design for developing Core Outcome Sets specifically for miscarriage trials.
  • To ensure that core outcome sets reflect the priorities of all key stakeholders, including patients and clinicians.
  • To improve the consistency and relevance of outcome reporting in miscarriage research.

Main Methods:

  • Systematic reviews, interviews, and focus groups will identify potential core outcomes.
  • A modified Delphi survey involving patients, partners, clinicians, charities, and researchers will be used.
  • Consensus will be reached through multiple rounds of scoring and face-to-face discussions.

Main Results:

  • The study details a robust methodology for developing Core Outcome Sets for miscarriage research.
  • The process ensures comprehensive stakeholder involvement to identify and prioritize key outcomes.
  • The developed Core Outcome Sets will facilitate more consistent and meaningful research findings.

Conclusions:

  • The development of Core Outcome Sets for Miscarriage Trials is essential for advancing research in this area.
  • These sets will enhance the comparability of trial results and reduce reporting bias.
  • Implementing these standardized outcomes can drive improvements in miscarriage care and services.