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Loose anagen syndrome.

V H Price1, C L Gummer

  • 1Department of Dermatology, Kaiser Permanente Medical Center, San Francisco, California.

Journal of the American Academy of Dermatology
|February 1, 1989
PubMed
Summary
This summary is machine-generated.

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Loose anagen syndrome is a hair condition where hairs are loosely anchored and easily pulled. This affects children and adults, causing sparse hair that doesn't grow long.

Area of Science:

  • Dermatology
  • Trichology
  • Pediatric Hair Disorders

Background:

  • Loose anagen syndrome (LAS) is a hair condition characterized by loosely anchored anagen hairs.
  • It primarily affects children, leading to sparse hair that is easily epilated.

Observation:

  • Patients present with sparse hair that does not attain significant length.
  • Easily epilated hairs are misshapen anagen hairs lacking external root sheaths.
  • Histological examination reveals abnormal premature keratinization in the inner root sheath.

Findings:

  • The study describes findings in 22 children and five adults with LAS.
  • While hair length and density improve with age, the loose anchoring persists into adulthood.
  • The condition affects both sexes and can occur in individuals with various hair colors, though blond girls aged 2-5 years are most commonly observed.

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Implications:

  • Understanding the pathophysiology of LAS aids in diagnosis and management.
  • Further research into the specific mechanisms of abnormal keratinization is warranted.
  • This condition highlights the complex factors influencing hair anchorage and growth cycles.