Related Experiment Video

Updated: Feb 18, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.7K

Poor agreement in questionnaire-based diagnostic criteria for adult atopic dermatitis is a challenge when examining

Y M F Andersen1,2,3, A Egeberg1,2, C R Hamann1,2,3

  • 1Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.

Allergy
|November 19, 2017
PubMed

Insights

This study explored the link between atopic dermatitis (AD) and cardio-metabolic risks in adults. Different diagnostic criteria yielded varied results, highlighting the need for better definitions in epidemiological studies.

Area of Science:

  • Epidemiology
  • Dermatology
  • Cardiology

Background:

  • The association between atopic dermatitis (AD) and cardio-metabolic risk factors remains unclear.
  • Currently, no validated questionnaire-based method exists to identify adults with AD.

Purpose of the Study:

  • To evaluate cardio-metabolic risk in adults with a history of AD.
  • To compare three distinct questionnaire-based diagnostic criteria for identifying AD in adults.

Main Methods:

  • Utilized data from a general population study of 9656 Danish adults.
  • Employed self-reported physician-diagnosed AD and two versions of the UK Working Party Diagnostic Criteria.
  • Applied survey-weighted logistic and linear regression to assess associations between AD status and cardio-metabolic endpoints.

Main Results:

  • Identified varying prevalence of AD based on diagnostic criteria (4.8% self-reported physician-diagnosed, 9.4% UK 2/4, 2.3% UK 3/4).
  • Observed heterogeneity in cardio-metabolic risk factors across different AD diagnostic groups, including obesity prevalence.
  • Populations identified by different criteria were not comparable regarding cardio-metabolic risk factors.

Conclusions:

  • No definitive conclusions on cardio-metabolic risk in adults with AD could be drawn due to population heterogeneity and lack of a gold standard.
  • The study underscores challenges in questionnaire-based epidemiological research for AD.
  • Highlights the critical need for improved definitions and diagnostic standards for atopic dermatitis in population studies.
Abstract

Keywords:
atopic dermatitiscardiovascular riskdiagnostic criteriaquestionnaire

More Related Videos

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

951
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

Related Concept Videos

Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
937
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
587
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
714
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.4K
Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
935