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Endocarditis due to Streptococcus morbillorum.

S Maxwell1

  • 1Department of Microbiology, Blackburn Royal Infirmary, U.K.

The Journal of Infection
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

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This study reports two rare cases of endocarditis caused by Streptococcus morbillorum in the UK. One strain showed significant resistance to beta-lactam antibiotics, requiring a combination therapy for effective treatment.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Endocarditis is a serious infection of the heart valves.
  • Streptococcus morbillorum is a rare cause of endocarditis, particularly in patients without pre-existing valvular disease.

Observation:

  • Two cases of Streptococcus morbillorum endocarditis are presented in the UK.
  • Neither patient had a history of valvular heart disease.
  • Potential initiating procedures included anal surgery and dental procedures.

Findings:

  • This is believed to be the first reported UK cases of endocarditis due to Streptococcus morbillorum.
  • The first case involved a strain with marked tolerance to beta-lactam antibiotics.
  • In vitro studies indicated a combination of penicillin and gentamicin was necessary for bactericidal activity.

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Implications:

  • Highlights Streptococcus morbillorum as a potential pathogen in endocarditis, even without valvular disease.
  • Underscores the need for susceptibility testing, as some strains may exhibit beta-lactam tolerance.
  • Suggests combination antibiotic therapy may be required for certain Streptococcus morbillorum infections.