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Related Experiment Video

Updated: Feb 18, 2026

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

Particle separation by phase modulated surface acoustic waves.

Gergely Simon¹, Marco A B Andrade², Julien Reboud³

¹Microsystems Engineering Centre, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, United Kingdom.

Biomicrofluidics

|November 21, 2017

Summary

This summary is machine-generated.

This study introduces an optimized acoustic phase modulation for high-efficiency particle separation in microfluidic devices. The novel method achieves superior selectivity and purity for cell and particle isolation.

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Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Area of Science:

Microfluidics
Acoustic manipulation
Biotechnology

Background:

Efficient cell and particle isolation is crucial for lab-on-a-chip devices.
Acoustic techniques offer label-free, contactless manipulation preserving cell viability.
Conventional methods have limited separation power due to slow force gradients.

Purpose of the Study:

To propose an optimized phase modulation scheme for particle separation in surface acoustic wave microfluidic devices.
To derive and analyze the acoustic radiation force in surface acoustic wave devices.
To experimentally validate the proposed method for high-selectivity particle separation.

Main Methods:

Theoretical derivation of acoustic radiation force, considering geometric scaling factors.
Investigation of two phase modulation schemes.
Experimental validation using polystyrene particle mixtures.
Monte-Carlo simulations to assess performance under real-world conditions.

Main Results:

Demonstrated a novel acoustic radiation force expression differing from bulk devices.
Achieved high selectivity and purity in separating polystyrene particles.
Validated the method's robustness against particle size variation and acoustic field non-uniformity.

Conclusions:

The optimized phase modulation scheme enables high-purity and high-resolution particle separation.
This technique enhances the capabilities of acoustic manipulation in microfluidic applications.
The findings contribute to advancing lab-on-a-chip device efficiency.