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Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis
I Wirguin1, E Shinar, O Abramsky
1Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.
Journal of Neurology
|January 1, 1989
Abstract:
In a small pilot study of plasmapheresis in chronic progressive multiple sclerosis, two patients suffered relapses following an acute allergic reaction to plasma. It is suggested that allergic reactions may have played a role in the exacerbation and recommended that fresh frozen plasma be avoided in therapeutic trials for multiple sclerosis.