Related Experiment Video
Updated: Feb 18, 2026
11:02
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
21.8K
Bladder Cancer Recovery Pathways: A Systematic Review
Ian Maloney1, Daniel C Parker1, Michael S Cookson1
1Department of Urology, The University of Oklahoma Health Sciences Center and The Stephenson Cancer Center, Oklahoma City, OK, USA.
Bladder Cancer (Amsterdam, Netherlands)
|November 21, 2017
Summary
Enhanced recovery pathways (ERPs) show promise for improving patient outcomes in major surgery. However, consistent implementation and proven cost reduction for radical cystectomy require further investigation.
Area of Science:
- Surgical Oncology
- Evidence-Based Medicine
- Health Services Research
Background:
- Enhanced recovery pathways (ERPs), or fast-track protocols, emerged in the early 2000s.
- ERPs aim to improve patient outcomes and reduce healthcare costs in major surgery.
Purpose of the Study:
- Review the origin and contemporary use of ERPs in radical cystectomy.
- Analyze ERP effects on morbidity, mortality, and treatment costs.
Main Methods:
- Comprehensive literature search of multiple electronic databases.
- Inclusion of randomized controlled trials and cohort studies on radical cystectomy.
- Assessment of study evidence strength using risk of bias, consistency, directness, and precision.
Main Results:
- 1,236 articles identified, 106 studies in 52 publications met inclusion criteria.
- Literature supports ERPs for improving patient morbidity and mortality.
- Standardization and adherence to ERPs are lacking across institutions.
Conclusions:
- ERPs are well-supported for improving patient morbidity and mortality.
- Lack of standardization and adherence hinders consistent implementation.
- Direct efficacy of ERPs in reducing preventable treatment expenditures remains unconfirmed.
