Related Experiment Video
Updated: Feb 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antimicrobial stewardship in pediatric post-acute care facilities
Candace L Johnson1, Meaghan Jain2, Lisa Saiman3
1Department of Pediatrics, Columbia University Medical Center, New York, NY.
Pediatric post-acute care providers recognize antibiotic overuse but struggle with implementation. Lack of treatment guidelines is a major barrier to antimicrobial stewardship programs in these facilities.
Area of Science:
- Pediatrics
- Infectious Diseases
- Healthcare Management
Background:
- Antimicrobial resistance is a growing global health threat.
- Appropriate antibiotic use is crucial in healthcare settings, especially for vulnerable pediatric populations.
- Pediatric post-acute care (PAC) facilities face unique challenges in managing antibiotic therapy.
Purpose of the Study:
- To assess the knowledge and resources related to antimicrobial stewardship among providers in pediatric PAC facilities.
- To identify barriers to the implementation of antimicrobial stewardship strategies in this setting.
Main Methods:
- A survey was distributed to healthcare providers in pediatric PAC facilities.
- The survey assessed awareness of antibiotic overuse and the existence of stewardship resources and strategies.
- Respondents identified challenges and barriers to implementing antimicrobial stewardship.
Main Results:
- All surveyed providers agreed that antibiotics are overused in pediatric PAC facilities.
- Despite agreement on overuse, 60% reported not having implemented any antimicrobial stewardship strategies.
- The most frequently cited barrier to implementing stewardship was the lack of specific treatment guidelines (47% of respondents).
Conclusions:
- There is a significant gap between recognizing the problem of antibiotic overuse and implementing solutions in pediatric PAC settings.
- The absence of clear treatment guidelines presents a critical obstacle to effective antimicrobial stewardship.
- Interventions focusing on guideline development and resource provision are needed to improve antibiotic use in pediatric PAC facilities.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Acute Pyelonephritis II: Diagnostic Studies and Management
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

