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Papillary glioneuronal tumors: A radiopathologic correlation
Nishtha Yadav1, Shilpa Rao2, Jitender Saini1
1Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore-560029, India.
European Journal of Radiology
|November 21, 2017
Summary
Papillary glioneuronal tumors (PGNT) are rare brain tumors. Neuroimaging showing a cystic mass with septations and a solid component in the periventricular region suggests PGNT.
Area of Science:
- Neuro-oncology
- Neuroradiology
- Pathology
Background:
- Papillary glioneuronal tumors (PGNT) represent a rare and recently identified category of brain neoplasms.
- Accurate preoperative diagnosis of PGNT is challenging due to their rarity.
Purpose of the Study:
- To review neuroimaging findings of histologically confirmed PGNT cases.
- To identify specific imaging features that may aid in the preoperative diagnosis of PGNT.
Main Methods:
- Retrospective review of seven histologically confirmed PGNT cases diagnosed between 2004 and 2014.
- Tabulation and analysis of clinical, neuroimaging, and histopathological findings.
Main Results:
- The majority of lesions were periventricular and located in the temporal lobe, presenting as solid-cystic or purely solid masses.
- Common findings included hemorrhage (71.4%) and calcification (42.9%).
- Key imaging features were contrast-enhancing septations within cystic components and heterogeneous enhancement of the solid component, correlating with pseudopapillary projections and increased cellularity, respectively.
Conclusions:
- The presence of a periventricular cystic mass with septations and a solid component on neuroimaging should raise suspicion for PGNT.
- Specific imaging characteristics can assist in differentiating PGNT from other brain tumors preoperatively.
