Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
3.7K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.3K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.3K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

3.5K
3.5K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

8.1K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
8.1K
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

1.5K
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cultivation, chemistry, and genome of <i>Psilocybe zapotecorum</i>.

Journal of psychedelic studies·2026
Same author

<i>Panaeolus oligotrophus</i>: A new species from central Florida, with notes on <i>Panaeolus pumilus</i> and <i>Crucispora rhombisperma</i>.

Mycologia·2025
Same author

High-quality draft genomes of ecologically and geographically diverse <i>Psilocybe</i> species.

Microbiology resource announcements·2024
Same author

CLOCI: unveiling cryptic fungal gene clusters with generalized detection.

Nucleic acids research·2024
Same author

Domestication through clandestine cultivation constrained genetic diversity in magic mushrooms relative to naturalized populations.

Current biology : CB·2023
Same author

Cultivation, chemistry, and genome of <i>Psilocybe zapotecorum</i>.

bioRxiv : the preprint server for biology·2023

Related Experiment Video

Updated: Feb 18, 2026

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure
10:33

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure

Published on: May 27, 2022

7.0K

Fungal Gene Cluster Diversity and Evolution.

Jason C Slot1

  • 1The Ohio State University, Columbus, OH, United States.

Advances in Genetics
|November 21, 2017
PubMed
Summary

Metabolic gene clusters (MGCs) in fungi provide insights into nutrient acquisition and metabolite synthesis. These clusters enhance fungal adaptability and survival through integrated regulatory and protective mechanisms.

Area of Science:

  • Mycology
  • Biochemistry
  • Genetics

Background:

  • Metabolic gene clusters (MGCs) are key to understanding biochemical processes in yeast and filamentous fungi.
  • These clusters encode mechanisms for nutrient acquisition and metabolite synthesis/degradation.
  • MGCs contribute to fungal adaptability and survival.

Purpose of the Study:

  • To explore the role of MGCs in fungal metabolism and adaptation.
  • To investigate the evolutionary origins and persistence of MGCs.
  • To highlight the importance of MGCs in fungal physiology and ecology.

Main Methods:

  • Phylogenetic analysis of MGC distribution.
  • Ecological pattern analysis of MGCs.
  • Review of gene cluster origins (duplication, relocation, horizontal transfer).
Keywords:
Gene clusterGenome evolutionHorizontal gene transferMetabolismPhylogeny

More Related Videos

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K
Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
05:34

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Published on: June 6, 2025

617

Related Experiment Videos

Last Updated: Feb 18, 2026

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure
10:33

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure

Published on: May 27, 2022

7.0K
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K
Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
05:34

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Published on: June 6, 2025

617

Main Results:

  • MGCs contain diverse genetic mechanisms for nutrient acquisition and metabolism.
  • MGCs possess self-protection and regulatory machinery, enhancing fungal adaptability.
  • MGC distribution patterns reflect fungal diversity in life cycles and nutrition.

Conclusions:

  • MGCs are crucial for fungal metabolic and ecological adaptability.
  • Studying MGCs aids in understanding fungal physiology, ecology, and evolution.
  • Gene clustering offers potential fitness advantages, though experimental evidence is limited.