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Updated: Feb 18, 2026

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Published on: October 18, 2024
Role of lung volume and airway inflammation in obstructive sleep apnea
Andras Bikov1, Gyorgy Losonczy1, Laszlo Kunos1
1Department of Pulmonology, Semmelweis University, Budapest, Hungary.
Abstract:
Obstructive sleep apnea (OSA) is a prevalent disorder that affects not only the upper airways but also the intrathoracic airways. In this review, we summarize the results of studies on lung function and airway inflammation. We provide evidence that the alterations in intrathoracic airways observed in OSA are not purely consequences of mechanical trauma and oxidative stress during apneic events but have a causal role in the structural changes associated with OSA and increasing severity of this disorder.
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