HeartMate III Left Ventricular Assist Device Thrombosis Triggered by an Automatic Implantable

Stefan Klotz1, Antje Karluss1, Sina Stock1

  • 1Department of Cardiac and Thoracic Vascular Surgery, University Hospital Schleswig-Holstein, Lübeck, Germany.

Insights

A left ventricular assist device (LVAD) thrombosis was triggered by an implantable cardioverter defibrillator shock, causing a clot to enter the device. Increased motor temperature and CT scans confirmed the issue, leading to successful pump exchange.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Left ventricular assist devices (LVADs) are crucial for end-stage heart failure management.
  • Implantable cardioverter defibrillators (ICDs) are used to treat life-threatening arrhythmias.
  • Co-implantation of LVADs and ICDs presents unique clinical challenges.

Observation:

  • A patient with a HeartMate III LVAD experienced device thrombosis.
  • The thrombosis was initiated by an electrical shock from an co-implanted automatic implantable cardioverter defibrillator (AICD).
  • The AICD shock released a left ventricular thrombus that was drawn into the LVAD inflow cannula.

Findings:

  • LVAD thrombosis was suspected due to unexplained low flow and increased pump motor temperature.
  • Computed tomography (CT) scan confirmed the presence of a thrombus within the LVAD inflow cannula.
  • The primary cause identified was the AICD-induced dislodgement of a left ventricular thrombus.

Implications:

  • This case highlights a rare but serious complication of combined LVAD and AICD therapy.
  • Device thrombosis management requires prompt diagnosis and intervention, such as pump exchange.
  • Further research may be needed to optimize strategies for preventing such device-related complications in patients with mechanical circulatory support.

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