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Post-irradiation vaginal spindle cell sarcoma.

A Kalogeraki1, C Ximeris1, V Ximeri1

  • 1Department of Pathology-Cytopathology, Medical School, University of Crete, University Hospital, Heraklion, Crete, Greece.

Pathologica
|November 21, 2017
PubMed
Summary
This summary is machine-generated.

Radiation therapy can lead to spindle cell sarcoma years later. This case highlights how Pap smears can diagnose this rare cancer, confirmed by histology and immunohistology.

Area of Science:

  • Oncology
  • Pathology
  • Genetics

Background:

  • Spindle cell sarcoma can arise secondary to genetic factors or prior irradiation.
Keywords:
CytologyHistologyImmunohistologyPost-irradiation sarcoma

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  • Radiotherapy for other cancers can induce genetic alterations, potentially leading to neoplasia.
  • Previous pelvic irradiation is a known risk factor for secondary malignancies.