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Updated: Feb 18, 2026

Quantitative Visualization of Leukocyte Infiltrate in a Murine Model of Fulminant Myocarditis by Light Sheet Microscopy
Published on: May 31, 2017
Acute fulminant necrotizing eosinophilic myocarditis: early diagnosis and treatment
Paul David Callan1, Aigul Baltabaeva1, Mohammed Kamal1
1Harefield Hospital, Hill End Road, Harefield, UB9 6JH, UK.
Abstract:
Necrotizing eosinophilic myocarditis is a rare but potentially fatal condition that requires prompt recognition and treatment. We describe a case of a young athlete presenting with chest pain and breathlessness, with evidence of rapidly deteriorating cardiac function. The condition was successfully treated with corticosteroids, with no evidence of residual myocardial damage. This is the first reported case to demonstrate the utility of cardiac magnetic resonance imaging for diagnosis and monitoring response to treatment. It also highlights the value of endomyocardial biopsy in establishing a tissue diagnosis in cases of fulminant myocarditis, in order to direct treatment appropriately.
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