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Updated: Feb 18, 2026

3D Whole-heart Myocardial Tissue Analysis
Published on: April 12, 2017
Contrast-enhanced computed tomography with myocardial three-dimensional printing can guide treatment in symptomatic
Yasuhiro Hamatani1, Makoto Amaki1, Hideaki Kanzaki1
1Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Insights
Surgical myectomy and septal ablation treat hypertrophic obstructive cardiomyopathy (HOCM). Contrast-enhanced CT and 3D models improve assessment for these complex HOCM cases.
Area of Science:
- Cardiology
- Medical Imaging
- Biomedical Engineering
Background:
- Drug-refractory symptomatic hypertrophic obstructive cardiomyopathy (HOCM) presents treatment challenges.
- Accurate anatomical assessment is crucial for selecting effective interventions like surgical myectomy or percutaneous transluminal septal myocardial ablation.
Observation:
- A young female patient with drug-refractory symptomatic HOCM required precise evaluation of left ventricular outflow obstruction.
- Contrast-enhanced computed tomography (CECT) was utilized to visualize complex cardiac structures.
- Three-dimensional (3D) printed models were generated from CECT data for enhanced spatial understanding.
Findings:
- CECT effectively assessed the suitability of percutaneous transluminal septal myocardial ablation in this HOCM case.
- 3D printed models facilitated detailed visualization of intracardiac anatomy and surgical simulation.
- A multimodality approach combining CECT and 3D modeling proved valuable.
Implications:
- This case highlights the utility of advanced imaging techniques in managing complex HOCM.
- Multimodality assessment strategies can improve treatment selection and procedural planning for HOCM patients.
- Integrating CECT and 3D modeling offers a promising approach for challenging HOCM cases.
Abstract:
Both surgical myectomy and percutaneous transluminal septal myocardial ablation are effective treatments for drug-refractory symptomatic hypertrophic obstructive cardiomyopathy (HOCM). However, in some cases, it is not easy to elucidate the abnormal structure of left ventricular outflow obstruction to adopt these treatments. Here, we presented a young female patient with drug-refractory symptomatic HOCM. In this case, contrast-enhanced computed tomography enabled us to assess the suitability of percutaneous transluminal septal myocardial ablation. By creating three-dimensional printed models using computed tomography data, we could also visualize intracardiac structure and simulate the surgical procedure. A multimodality assessment strategy is useful for evaluating patients complicated with drug-refractory symptomatic HOCM.
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