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Use of Human Perivascular Stem Cells for Bone Regeneration
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Legg-Calvé-Perthes disease
J Leroux1, S Abu Amara1, J Lechevallier1
1Clinique chirurgicale infantile, hôpital Charles-Nicolle, centre hospitalier universitaire (CHU) de Rouen, 1, rue de Germont, Rouen 76031, France.
Orthopaedics & Traumatology, Surgery & Research : OTSR
|November 21, 2017
Summary
Effective Legg-Calvé-Perthes disease (LCPD) prevention remains elusive. Surgical interventions like osteotomy offer good outcomes for specific LCPD cases, while others benefit from watchful waiting.
Area of Science:
- Orthopedics
- Pediatric Orthopedics
- Hip Preservation Surgery
Background:
- Legg-Calvé-Perthes disease (LCPD) lacks effective preventive strategies due to incomplete understanding of causes and risk factors.
- Adult outcomes for LCPD are generally favorable, with hip osteoarthritis typically developing after age 50, influenced by joint incongruence.
Conclusions:
- Therapeutic abstention is advised for LCPD cases not meeting specific criteria for surgical intervention.
- Surgical management of LCPD should be guided by prognostic factors like age and lateral pillar classification.
- Optimal surgical techniques vary based on LCPD severity, with combined or triple pelvic osteotomies indicated for advanced disease.
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