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Elderly patients with glomerular diseases and IgA nephropathy.

Jing Lin1,2, Zhen Cheng3,2, Qi Qian2

  • 1Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.

Nephrology (Carlton, Vic.)
|November 21, 2017
PubMed
Summary

Kidney diseases, including IgA nephropathy, are increasing in the elderly. More research is needed on kidney biopsy and treatment strategies for older adults with kidney conditions.

Keywords:
IgA nephropathyelderlyglomerular diseaseskidney biopsy for elderlyrisk prediction

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Area of Science:

  • Nephrology
  • Geriatric Medicine
  • Pathology

Background:

  • The global population is aging, leading to a higher prevalence of kidney diseases in elderly patients.
  • Kidney diseases, such as IgA nephropathy, often necessitate kidney biopsy for accurate diagnosis, treatment planning, and prognosis.
  • Current clinical management strategies for elderly patients with kidney diseases are largely based on data from younger adult populations.

Purpose of the Study:

  • To review the current and future healthcare landscape concerning kidney diseases in the aging population.
  • To analyze the advantages and disadvantages of kidney biopsy in elderly individuals.
  • To examine treatment strategies, precautions, and available data on IgA nephropathy in the elderly.

Main Methods:

  • Literature review focusing on kidney diseases in the elderly, IgA nephropathy, and kidney biopsy.
  • Analysis of clinicohistopathological features and differentiation of IgA nephropathy from IgA-dominant postinfectious glomerulonephritis.
  • Evaluation of treatment options and outcome prediction in elderly patients.

Main Results:

  • Data on kidney diseases, including IgA nephropathy, in advanced age are limited.
  • Clinical and management approaches are often extrapolated from studies on younger adults.
  • Specific occurrence rates, clinicohistopathological features, and treatment outcomes for IgA nephropathy in the elderly require further investigation.

Conclusions:

  • There is a significant need for age-specific clinical and translational research into kidney diseases affecting the elderly population.
  • Kidney biopsy remains a crucial tool for managing kidney diseases in older adults, despite potential challenges.
  • Optimizing the diagnosis and treatment of kidney diseases in the elderly requires dedicated research efforts tailored to this demographic.