Related Experiment Video
Updated: Feb 18, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Hepatic Imaging in Neonates and Young Infants: State of the Art
Stephanie B Shamir1, Jessica Kurian1, Debora Kogan-Liberman1
1From the Department of Radiology, Montefiore Medical Center and Albert Einstein College of Medicine, 111 E 210 St, Bronx, NY 10467.
Insights
Neonatal liver disease presents unique challenges in infants, requiring specialized imaging interpretation. This review covers key pathologies and imaging techniques for prompt diagnosis in neonates.
Area of Science:
- Pediatric Radiology
- Neonatal Hepatology
- Medical Imaging
Background:
- Neonatal liver disease is a significant cause of illness in infants.
- Disease presentation and diagnoses in neonates differ from older children.
- Imaging is crucial for diagnosis and preventing complications.
Purpose of the Study:
- To review liver pathologies in infants within the first six months of life.
- To educate general radiologists on interpreting neonatal liver imaging.
- To provide a systematic approach to neonatal liver ultrasound interpretation.
Main Methods:
- Review of cholestatic diseases, tumors, vascular anomalies, and acquired liver diseases.
- Discussion of optimized ultrasonography (US) and magnetic resonance imaging (MRI) techniques.
- Presentation of a systematic interpretation method for neonatal liver US.
Main Results:
- Neonatal liver pathologies encompass cholestatic, neoplastic, vascular, and acquired conditions.
- Optimized US and MRI are essential for accurate diagnosis.
- Integrating imaging findings with clinical and laboratory data is key.
Conclusions:
- Radiologists must be familiar with unique neonatal liver diseases.
- Prompt diagnosis through appropriate imaging is critical for patient outcomes.
- A systematic approach aids in accurate interpretation of neonatal liver imaging.
Abstract:
Neonatal liver disease is an important source of morbidity in the pediatric population. The manifestation of liver disease in young infants may be different than in older patients, and there are a number of diagnoses that are unique to this age group. Familiarity with these entities is important as imaging plays a key role in the diagnostic workup, and prompt diagnosis is necessary to prevent complications. This article reviews the spectrum of liver pathologies that can manifest in the first 6 months of life and is intended to educate the general radiologist who may be faced with interpretation of neonatal liver imaging. Categories of disease that will be reviewed include cholestatic diseases, tumors, vascular anomalies, and acquired diseases. The authors will also review optimization of ultrasonography (US) and magnetic resonance imaging of the liver and present a systematic method for interpretation of neonatal liver US findings in the context of clinical and laboratory findings. © RSNA, 2017.
Related Concept Videos
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VII: Vascular Imaging
Imaging Studies I: Kidney, Ureter, and Bladder Studies

