Related Experiment Video
Updated: Feb 18, 2026
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Risk factors for recurrent central line-associated bloodstream infections in a pediatric intensive care unit
Insights
Delaying central venous catheter reinsertion for at least 4 days after negative cultures and using polyurethane dressings can help prevent recurrent central line-associated bloodstream infections (CLABSI) in pediatric intensive care units.
Area of Science:
- Pediatric Intensive Care
- Infectious Disease Control
- Medical Device Management
Background:
- Central venous catheters (CVCs) require removal upon diagnosis of central line-associated bloodstream infection (CLABSI).
- Recurrent CLABSI poses a significant risk in pediatric patients with reinserted CVCs.
Purpose of the Study:
- To identify risk factors associated with recurrent CLABSI in pediatric patients with reinserted CVCs.
- To evaluate the impact of catheter management and reinsertion timing on CLABSI recurrence.
Main Methods:
- Retrospective study comparing patients with recurrent and non-recurrent CLABSI.
- Analysis of catheter exchange intervals, time to CVC reinsertion post-negative culture, and pre-/reinsertion treatment durations.
- Logistic regression to determine risk factors for recurrent CLABSI.
Main Results:
- 38.7% of patients with reinserted CVCs experienced recurrent CLABSI.
- Shorter intervals for catheter exchange, CVC reinsertion, and treatment were observed in the recurrent CLABSI group.
- Reinserting CVCs less than 4 days after negative cultures increased recurrent CLABSI risk 1.7-fold (P=0.021).
- Polyurethane dressings were associated with longer cumulative catheter dwell times compared to sterile gauze (P=0.005).
Conclusions:
- Delaying CVC reinsertion for at least 4 days post-negative culture is crucial for preventing recurrent CLABSI.
- Utilizing transparent polyurethane dressings over sterile gauze for CVC maintenance may reduce CLABSI recurrence.
- Optimizing CVC management protocols can mitigate the risk of recurrent bloodstream infections in pediatric ICUs.
Abstract:
Background/aim: It is recommended that a central venous catheter (CVC) be removed if central line-associated bloodstream infection (CLABSI) has been diagnosed. The objective of this retrospective study was to evaluate the risk factors for recurrent CLABSI in reinserted catheters in a pediatric intensive care unit. Materials and methods: Patients with recurrent and nonrecurrent CLABSI were compared in terms of the catheter exchange interval, the interval between negative blood culture and reinsertion of the CVC, and the pre-/reinsertion treatment duration. Results: Thirty-one patients with initial CLABSI had reinserted CVCs, and 12 (38.7%) of these patients were diagnosed with recurrent CLABSI. In the recurrent group, the catheter exchange interval, the interval between negative blood culture and reinsertion of the second CVC, and pre-/reinsertion treatment duration were found to be shorter. Logistic regression analysis revealed that if the interval between negative blood culture and reinsertion of the second CVC was shorter than 4 days, recurrent CLABSI risk increased by 1.7-fold (P = 0.021). Sterile gauze-dressed patients had shorter cumulative catheter surveys than the polyurethane-dressed patients (P = 0.005). Conclusion: Using transparent polyurethane dressings instead of sterile gauze for maintaining the CVC and delaying the reinsertion procedure for at least 4 days after the negative culture might be helpful in preventing recurrent CLABSI.
Related Concept Videos
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:29Endocarditis IV: Nursing Management
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
01:27Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...