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Sleep in children with type 1 diabetes and their parents in the T1D Exchange
Sarah S Jaser1, Nicole C Foster2, Bryce A Nelson3
1Vanderbilt University Medical Center, 1211 Medical Center Dr., Nashville, TN 37232, USA.
Insights
Poor sleep quality in children with type 1 diabetes is common and linked to worse glycemic control and increased risk of severe hypoglycemia and diabetic ketoacidosis. Addressing child sleep may improve outcomes and reduce parental distress.
Area of Science:
- Pediatric Endocrinology
- Sleep Medicine
- Metabolic Disorders
Background:
- Sleep disturbances are prevalent in children with type 1 diabetes (T1D).
- The impact of sleep on T1D management and family well-being is not well understood.
Purpose of the Study:
- To characterize sleep patterns in children with T1D and their parents.
- To examine associations between child sleep, glycemic control, adherence, and parental factors.
Main Methods:
- Surveys were distributed to parents of children aged 2-12 years in the T1D Exchange clinic registry.
- Clinical data were collected from 515 respondents.
Main Results:
- 67% of children experienced poor sleep quality, associated with poorer glycemic control (HbA1c) and increased risk of severe hypoglycemia and diabetic ketoacidosis (DKA).
- Poor child sleep quality correlated with reduced parental sleep quality, well-being, and increased fear of hypoglycemia.
- No association was found between child sleep and blood glucose monitoring frequency or diabetes technology use (CGM, insulin pump).
Conclusions:
- Sleep quality is a significant factor in pediatric type 1 diabetes management.
- Improving sleep in children with T1D may be a targetable intervention for enhancing glycemic control and alleviating parental distress.
Objectives:
Sleep has physiological and behavioral impacts on diabetes outcomes, yet little is known about the impact of sleep disturbances in children with type 1 diabetes. The current study sought to characterize sleep in children with type 1 diabetes and in their parents and to examine the associations between child sleep, glycemic control and adherence, parent sleep and well-being, parental fear of hypoglycemia, and nocturnal caregiving behavior.
Methods:
Surveys were emailed to parents of 2- to 12-year-old participants in the Type 1 Diabetes (T1D) Exchange clinic registry. Clinical data were obtained from the registry for the 515 respondents.
Results:
In our sample, 67% of children met criteria for poor sleep quality. Child sleep quality was related to glycemic control (HbA1c of 7.9% [63 mmol/mol] in children with poor sleep quality vs 7.6% [60 mmol/mol] in children with non-poor sleep quality; P < 0.001) but not mean frequency of blood glucose monitoring (BGM) (7.6 times/day vs 7.4 in poor/non-poor quality; P = 0.56). Associations were similar for sleep duration. Children with poor sleep quality were more likely to experience severe hypoglycemia (4% in children with poor sleep quality vs 1% in children with non-poor sleep quality; P = 0.05) and more likely to experience DKA (7% vs 4%, respectively; P < 0.001). Poorer child sleep quality was associated with poorer parental sleep quality, parental well-being, and fear of hypoglycemia (P < 0.001 for all). Child sleep was not related to the use of diabetes-related technology (CGM, insulin pump).
Conclusions:
Sleep may be a modifiable factor to improve glycemic control and reduce parental distress.
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