Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

632
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
632
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

815
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
815
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

1.2K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.2K
Ventilatory Modes01:14

Ventilatory Modes

1.7K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
1.7K
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

3.0K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
3.0K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

417
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
417

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Short term heart transplant outcomes with heart organ procurement services.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Clinical Characteristics and Outcomes in Intra-aortic Balloon Pump-Supported Cardiogenic Shock Among Patients Transferred to Tertiary Care Centers.

Journal of the Society for Cardiovascular Angiography & Interventions·2026
Same author

Resection of Intrapericardial Lymphangioma Invasive to Ventricular Apex via Left Anterolateral Thoracotomy.

Annals of thoracic surgery short reports·2026
Same author

Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry.

JACC. Advances·2026
Same author

A retrospective pilot crossover study of protocolized transition from inhaled nitric oxide to inhaled epoprostenol in adult cardiothoracic surgery.

JHLT open·2026
Same author

Two-Year Results of PROACTIVE-HF Trial Stratified by Left Ventricular Ejection Fraction.

Journal of cardiac failure·2026

Related Experiment Video

Updated: Feb 18, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

10.0K

Biventricular Support With Intracorporeal, Continuous Flow, Centrifugal Ventricular Assist Devices.

Francisco A Arabía1, Carmelo A Milano2, Claudius Mahr3

  • 1Cedars-Sinai Medical Center, Los Angeles, California.

The Annals of Thoracic Surgery
|November 22, 2017
PubMed
Summary

Biventricular assist devices using continuous flow pumps show high rates of adverse events and mortality in advanced heart failure patients. Further research is needed to improve outcomes for these complex cases.

More Related Videos

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.4K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

4.2K

Related Experiment Videos

Last Updated: Feb 18, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

10.0K
Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.4K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

4.2K

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Right ventricular dysfunction occurs in 10-30% of patients post-left ventricular assist device (LVAD) implantation.
  • Biventricular assist device (BiVAD) support is associated with higher mortality than LVAD alone.
  • Optimal BiVAD configuration for advanced heart failure remains undetermined.

Purpose of the Study:

  • To evaluate survival outcomes and adverse event frequency in patients receiving two durable, intracorporeal, continuous flow centrifugal pumps for biventricular support.

Main Methods:

  • A cohort of 38 adult patients receiving BiVAD support between November 2012 and June 2015 was identified from the INTERMACS registry.
  • Patients with dilated cardiomyopathy (idiopathic or ischemic) were the primary diagnoses.
  • Exclusion criteria included pediatric patients.

Main Results:

  • Survival rates were 68% at 6 months and 62% at 12 months.
  • High rates of adverse events were observed: infection (50%), bleeding (44%), respiratory failure (31.6%), and device malfunction (26.3%).
  • 11 patients died with the device in place, while 9 received a heart transplant.

Conclusions:

  • Durable, continuous flow centrifugal pumps for biventricular support are linked to significant morbidity and mortality.
  • This device configuration requires further investigation for improved management of advanced biventricular heart failure.