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Updated: Feb 18, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Gastric and Rectal Metastases from Malignant Melanoma Presenting with Hypochromic Anemia and Treated with
Pietro Genova1, Maria Sorce2, Daniela Cabibi3
1Surgical Oncology Unit, Dipartimento di Scienze Chirurgiche, Oncologiche e Stomatologiche, University of Palermo, Palermo, Italy.
Abstract:
The authors present a case of an 80-year-old Caucasian male with multiple gastric and rectal metastases from malignant melanoma presenting with hypochromic anemia as the sole symptom of disease without evidence of cutaneous and ocular tumor localization. The patient had a medical history positive for malignant lentigo melanoma of the occipital region of the scalp and early stage laryngeal squamous cell carcinoma and prostatic carcinoma treated with radiation therapy. The authors make some considerations on intestinal involvement by metastatic melanoma and discuss the choice of not treating with endoscopic procedures the gastric metastatic lesions most likely responsible for the clinical sign present at diagnosis. The patient was referred to clinical oncologists and received immunotherapy with ipilimumab and pembrolizumab.
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