Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Management of Insomnia01:19

Management of Insomnia

688
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
688
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

974
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
974
Analgesia and Pain Management01:25

Analgesia and Pain Management

2.1K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.1K
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

633
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
633
Drugs Affecting Neurotransmitter Synthesis01:29

Drugs Affecting Neurotransmitter Synthesis

2.3K
Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and carbidopa target specific enzymes involved in catecholamine synthesis. α-methyltyrosine inhibits the enzyme tyrosine hydroxylase, which converts tyrosine into dopamine. By blocking this enzyme, α-methyltyrosine reduces dopamine production and other catecholamines. Carbidopa, on the other hand, inhibits the enzyme dopa decarboxylase,...
2.3K
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

1.2K
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

College students' migraine perceptions and lived experiences: A qualitative study.

Headache·2026
Same author

Biomolecular condensates in living systems: from function to disease. What to do next.

Biophysical reviews·2026
Same author

Sex Education for HIV Prevention Among Adolescents and Young Adults (15-24 Years) Across Diverse Settings: An Integrative Review.

The Journal of the Association of Nurses in AIDS Care : JANAC·2026
Same author

Predictors of response to biofeedback-assisted relaxation for migraine: An exploratory analysis.

Cephalalgia : an international journal of headache·2026
Same author

Digital Assessment of Objective and Patient-Reported Cognition Across Migraine Phases: Results from the MIND Cohort.

medRxiv : the preprint server for health sciences·2026
Same author

Patient and Provider Experiences With Precision Oncology: Qualitative Descriptive Study at the Department of Veterans Affairs.

JMIR cancer·2026

Related Experiment Video

Updated: Feb 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.8K

Meta-Synthesis on Migraine Management.

Mia T Minen1, Carlita Anglin2, Alexandra Boubour3

  • 1NYU Langone Headache Center, New York, NY, USA.

Headache
|November 22, 2017
PubMed
Summary

Migraine patients face challenges with healthcare access, provider relationships, and treatment options. Qualitative research highlights the need for improved understanding and expanded support systems for better migraine management.

Keywords:
health care utilizationmanagementmigraineprovider rolequalitative researchsocietal implications

More Related Videos

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.3K
Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro
16:13

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Published on: June 13, 2011

20.5K

Related Experiment Videos

Last Updated: Feb 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.8K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.3K
Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro
16:13

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Published on: June 13, 2011

20.5K

Area of Science:

  • Medical Research
  • Qualitative Health Research
  • Patient-Reported Outcomes

Background:

  • Migraine is a leading cause of disability globally, impacting millions of adults.
  • Quantitative research often focuses on adherence and stigma, leaving patient perspectives under-explored.
  • Qualitative studies offer deeper insights into the lived experiences of migraine patients.

Purpose of the Study:

  • To synthesize qualitative research on migraine patients' treatment perspectives.
  • To identify common themes across diverse migraine treatment studies.
  • To inform future research directions in migraine care.

Main Methods:

  • Systematic literature search of qualitative studies on migraine treatment.
  • Searches conducted across multiple databases (PubMed, PsycINFO, EMBASE, etc.) from 1996-2016.
  • Thematic analysis of ten included studies involving 161 adult migraine patients.

Main Results:

  • Key themes include difficulties with healthcare utilization (cost, access) and perceived patient-provider relationships (trust, knowledge).
  • Patients expressed varied thoughts on treatments, including aversion to medications and interest in non-pharmacological options.
  • Societal implications, such as feeling dismissed and quality of life issues, were significant patient concerns.

Conclusions:

  • Metasynthesis reveals commonalities in patient perspectives on migraine treatment.
  • Recommends standardized reporting of inclusion criteria (e.g., ICHD, headache days) in qualitative migraine research.
  • Suggests exploring expanded roles for allied health professionals to improve patient outcomes.