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Serum homocysteine levels in acne patients
Hao Jiang1, Changyi Li1, Bin Wei2
1Department of Dermatology, Clinical Research Center, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
Objective:
This study was designed to investigate serum homocysteine (HCY) levels in acne patients.
Methods:
Acne patients (n = 124) and healthy volunteers (n = 70), matched in terms of both age and sex, were enrolled. Serum HCY levels for all subjects were measured by a clinical laboratory.
Results:
Serum HCY levels in male and female patients with severe and moderate acne were significantly higher than in the healthy control group (P < .05). The constituent ratio of male and female acne patients with HCY above the normal range (10 mmol/L) was significantly higher than the healthy control group. The severity of acne patients was positively correlated with serum homocysteine concentration, (P < .01).
Conclusion:
Hyperhomocysteinemia may be an independent risk factor for acne vulgaris. Detection of serum HCY is important for acne patients.
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