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Bleomycin-induced flagellate erythema after venous malformation sclerosis-Case report and brief review
Cristina Pinto1, Concepción Lorca-Garcia2, Beatriz Berenguer2
1Department of Plastic and Reconstructive Surgery, Centro Hospitalar de Vila Nova de Gaia/Espinho and Hospital da Prelada, Porto, Portugal.
Abstract:
Bleomycin-induced flagellate erythema is a rare but typical skin toxicity of bleomycin. We report the case of a boy with a left foot venous malformation who developed this skin rash after two sessions of bleomycin intralesional injection. We discuss the mechanism and characteristics of this reaction to bleomycin, which is usually benign and self-limited. We conclude that, although rare, flagellate pigmentation can occur when bleomycin is used as a sclerosant in children.
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