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Exceptional response to brivaracetam in a patient with refractory idiopathic generalized epilepsy and absence
Alberto Grande-Martín1, David Sopelana-Garay2, José Manuel Pardal-Fernández3
1Department of Neurology,, Department of Clinical Neurophysiology, General Hospital of Albacete, Spain.
Abstract:
Brivaracetam is currently indicated as adjunctive therapy for patients with focal-onset seizures with or without secondary generalization. However, it has been suggested that it could provide broad-spectrum efficacy given its similarity to levetiracetam and based on the results from preclinical studies and others of patients with generalized epilepsy. We present the case of a woman with refractory idiopathic generalized epilepsy and absence seizures with dramatic response to brivaracetam. Our report supports a consideration of treatment with this new antiepileptic drug on a case-by-case basis in patients with refractory generalized epilepsy, while we await further studies on this topic.
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