Related Experiment Video
Updated: Aug 13, 2026

Electroporation of Craniofacial Mesenchyme
Published on: November 28, 2011
Infectious complications of craniofacial surgery in children
1Department of Pediatrics, University of Texas Health Science Center, Dallas 75235.
Insights
Craniofacial surgery in children can lead to infections, especially with combined monoblock repairs. Staged procedures are recommended to reduce infection risks in pediatric craniofacial surgery.
Area of Science:
- Plastic Surgery
- Pediatric Surgery
- Craniofacial Surgery
Background:
- Congenital anomalies often require complex oromaxillary and craniofacial surgical interventions in children.
- Postoperative infectious complications are a significant concern in pediatric craniofacial surgery.
Purpose of the Study:
- To analyze the incidence of infectious complications in pediatric oromaxillary and craniofacial surgeries.
- To identify risk factors associated with postoperative infections in craniofacial procedures.
Main Methods:
- Retrospective review of 219 pediatric patients undergoing oromaxillary or craniofacial surgery between 1975 and 1984.
- Multivariate discriminant analysis to identify predictors of postoperative infection.
- Comparison of infection rates across different surgical approaches (oromaxillary, intracranial, extracranial, combined monoblock).
Main Results:
- No infections occurred after 56 oromaxillary procedures.
- The overall infection rate for craniofacial surgery was 14.7% (24/163).
- Combined monoblock repairs had a significantly higher infection rate (45%) compared to intracranial (8%) or extracranial (5%) procedures alone.
- Key predictors of infection included operation length, procedure type, and patient age.
Conclusions:
- Combined monoblock craniofacial repairs are associated with a substantially increased risk of postoperative infection in pediatric patients.
- Staged surgical approaches are recommended to minimize infection rates in craniofacial surgery.
- Careful consideration of operative time, procedure type, and patient age is crucial for managing infection risk.
Abstract:
During the 10-year period 1975 through 1984, 219 children with congenital anomalies underwent oromaxillary or craniofacial surgery at Children's Medical Center, Dallas. There were no infectious complications following 56 oromaxillary procedures. The overall rate of infection following craniofacial surgery was 14.7% (24 of 163). Infection rates were significantly increased when a combined (monoblock) repair was performed (45% [15 of 33]), compared with either intracranial (8% [six of 72]) or extracranial (5% [three of 58]) procedures alone (P less than .001). The variables identified by multivariate discriminant analysis as useful independent predictors of postoperative infection were, in order of decreasing importance: length of operation, type of procedure (intracranial, extracranial, or combined), and age. Staged procedures are recommended for craniofacial surgery whenever possible because of the significant increase in rate of infection associated with the monoblock repair.
More Related Videos
04:04Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
08:03Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Brain Abscess l: Introduction