ESI MS for Microsized Bioparticles
Abdil Ozdemir1, Jung-Lee Lin2, Mustafa Gulfen1
1Department of Chemistry, Faculty of Arts and Sciences, Sakarya University , Esentepe, 54187 Sakarya, Turkey.
Analytical Chemistry
|November 22, 2017
Abstract:
An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.
