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Author Spotlight: Investigating the Underlying Mechanisms of Right Ventricular Failure in Pulmonary Hypertension
Published on: June 14, 2024
Right Ventricular Function is Important for Pulmonary Artery Banding in Left Ventricular Dysfunction
Lloyd M Felmly1, Andrew J Savage2, Minoo N Kavarana1
1Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC, USA.
Insights
Reversible pulmonary artery banding (rPAB) offers a potential treatment for infants with severe left ventricular dysfunction (LVD). Patient selection is crucial, as one infant improved while another required transplantation.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Neonatal Medicine
Background:
- Severe left ventricular dysfunction (LVD) in infants presents significant challenges with limited treatment options.
- Current definitive therapies include mechanical support and heart transplantation, often with high morbidity and mortality.
- Reversible pulmonary artery banding (rPAB) has emerged as a potential strategy to improve ventricular function.
Abstract:
Small infants with severe left ventricular dysfunction (LVD) carry a poor prognosis with limited therapeutic options. Although mechanical support and heart transplantation are definitive therapies, improvement of left ventricular function with reversible pulmonary artery banding (rPAB) has been described. We report two cases of LVD treated with rPAB. One was successfully temporized, and one progressed to requiring transplantation, indicating that appropriate patient selection is critical to this technique's success.
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