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Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

810
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Related Experiment Video

Updated: Feb 18, 2026

Author Spotlight: Investigating the Underlying Mechanisms of Right Ventricular Failure in Pulmonary Hypertension
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Author Spotlight: Investigating the Underlying Mechanisms of Right Ventricular Failure in Pulmonary Hypertension

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Right Ventricular Function is Important for Pulmonary Artery Banding in Left Ventricular Dysfunction.

Lloyd M Felmly1, Andrew J Savage2, Minoo N Kavarana1

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC, USA.

World Journal for Pediatric & Congenital Heart Surgery
|November 23, 2017
PubMed
Summary

Reversible pulmonary artery banding (rPAB) offers a potential treatment for infants with severe left ventricular dysfunction (LVD). Patient selection is crucial, as one infant improved while another required transplantation.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Neonatal Medicine

Background:

Keywords:
ECMO (extracorporeal membrane oxygenation)heart failurepulmonary artery bandtransplantation

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  • Severe left ventricular dysfunction (LVD) in infants presents significant challenges with limited treatment options.
  • Current definitive therapies include mechanical support and heart transplantation, often with high morbidity and mortality.
  • Reversible pulmonary artery banding (rPAB) has emerged as a potential strategy to improve ventricular function.