Related Experiment Video
Updated: Feb 18, 2026

Bilateral Renal Ischemia-Reperfusion Model for Acute Kidney Injury in Mice
Published on: February 2, 2024
The R.I.R.S. scoring system: An innovative scoring system for predicting stone-free rate following retrograde
Yinglong Xiao1, Deng Li2, Lei Chen2
1Department of Urology, Shanghai General Hospital of Nanjing Medical University, No.100, Haining Road, Hongkou District, Shanghai, 200080, China.
Background:
To establish and internally validate an innovative R.I.R.S. scoring system that allows urologists to preoperatively estimate the stone-free rate (SFR) after retrograde intrarenal surgery (RIRS).
Methods:
This study included 382 eligible samples from a total 573 patients who underwent RIRS from January 2014 to December 2016. Four reproducible factors in the R.I.R.S. scoring system, including renal stone density, inferior pole stone, renal infundibular length and stone burden, were measured based on preoperative computed tomography of urography to evaluate the possibility of stone clearance after RIRS.
Results:
The median cumulative diameter of the stones was 14 mm, and the interquartile range was 10 to 21. The SFR on postoperative day 1 in the present cohort was 61.5% (235 of 382), and the final SFR after 1 month was 73.6% (281 of 382). We established an innovative scoring system to evaluate SFR after RIRS using four preoperative characteristics. The range of the R.I.R.S. scoring system was 4 to 10. The overall score showed a great significance of stone-free status (p < 0.001). The area under the receiver operating characteristic curve of the R.I.R.S. scoring system was 0.904.
Conclusions:
The R.I.R.S. scoring system is associated with SFR after RIRS. This innovative scoring system can preoperatively assess treatment success after intrarenal surgery and can be used for preoperative surgical arrangement and comparisons of outcomes among different centers and within a center over time.
Related Concept Videos
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Acute Kidney Injury I: Introduction
Urinary Tract Calculi III: Medical Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Urinary Tract Calculi VI: Surgical Management
Urinary Tract Calculi V: Nursing Management

