Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic impact of sarcopenia and its correlation with circulating miR-21 in colorectal cancer patients.

Oncology reports·2018
Same author

Diagnosis of lymphoepithelial carcinoma in parotid gland with three dimensional computed tomography angiography reconstruction: A case report.

Journal of X-ray science and technology·2018
Same author

Association between structural and functional brain alterations in drug-free patients with schizophrenia: a multimodal meta-analysis.

Journal of psychiatry & neuroscience : JPN·2018
Same author

Dental pulp stem cell-derived chondrogenic cells demonstrate differential cell motility in type I and type II collagen hydrogels.

The spine journal : official journal of the North American Spine Society·2018
Same author

Neuronalinjury and roles of apoptosis and autophagy in a neonatal rat model of hypoxia-ischemia-induced periventricular leukomalacia.

Molecular medicine reports·2018
Same author

Functional brain abnormalities in major depressive disorder using the Hilbert-Huang transform.

Brain imaging and behavior·2018
Same journal

Assessing circuit function in the developing <i>Xenopus</i> tadpole: a survey of the behavioral toolkit and underlying neural substrates.

Frontiers in behavioral neuroscience·2026
Same journal

Dawn of the dread: threatening cinematic virtual reality environments enhance general but not specific pavlovian-instrumental transfer.

Frontiers in behavioral neuroscience·2026
Same journal

Transcranial alternating current stimulation improves cognitive functions in healthy subjects through modifying frontoparietal and dorsal attention networks based on personalized individual theta frequency analysis.

Frontiers in behavioral neuroscience·2026
Same journal

Functional loss of PKMζ in the dorsal hippocampus potentiates the time-dependent increase in false contextual fear memory and impairs spatial recognition memory in mice.

Frontiers in behavioral neuroscience·2026
Same journal

Distinct orbitofrontal circuits with dorsal and ventral CA1 differentially regulate spatial memory and emotional behaviors.

Frontiers in behavioral neuroscience·2026
Same journal

Towards a neurophysiological model of kundalini: a theoretical framework informed by preliminary clinical observations.

Frontiers in behavioral neuroscience·2026
See all related articles

Related Experiment Video

Updated: Feb 18, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

5.1K

Localized Fluctuant Oscillatory Activity by Working Memory Load: A Simultaneous EEG-fMRI Study.

Xiaojie Zhao1, Xiaoyun Li1, Li Yao1

  • 1College of Information Science and Technology, Beijing Normal University, Beijing, China.

Frontiers in Behavioral Neuroscience
|November 23, 2017
PubMed
Summary
This summary is machine-generated.

This study reveals how working memory load impacts brain activity. Increased load modulates electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) signals in specific brain regions during cognitive tasks.

Keywords:
event-related spectral perturbationfMRIjoint independent component analysismemory loadoscillation

More Related Videos

Conducting Concurrent Electroencephalography and Functional Near-Infrared Spectroscopy Recordings with a Flanker Task
13:18

Conducting Concurrent Electroencephalography and Functional Near-Infrared Spectroscopy Recordings with a Flanker Task

Published on: May 24, 2020

8.3K
Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

21.2K

Related Experiment Videos

Last Updated: Feb 18, 2026

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI
11:00

Reliable Acquisition of Electroencephalography Data during Simultaneous Electroencephalography and Functional MRI

Published on: March 19, 2021

5.1K
Conducting Concurrent Electroencephalography and Functional Near-Infrared Spectroscopy Recordings with a Flanker Task
13:18

Conducting Concurrent Electroencephalography and Functional Near-Infrared Spectroscopy Recordings with a Flanker Task

Published on: May 24, 2020

8.3K
Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

21.2K

Area of Science:

  • Cognitive Neuroscience
  • Neuroimaging
  • Electrophysiology

Background:

  • Working memory (WM) is crucial for cognitive tasks, but its neural mechanisms under varying loads are not fully understood.
  • Previous studies using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) offer insights but lack integrated analysis of their temporal and spatial dynamics.
  • The relationship between EEG oscillations and fMRI-detected brain activation during cognitive load remains an area requiring further investigation.

Purpose of the Study:

  • To investigate the neural mechanisms underlying working memory load by simultaneously analyzing EEG and fMRI data.
  • To explore how different frequency bands in EEG and brain activation patterns in fMRI change with increasing working memory load.
  • To elucidate the temporal dynamics and spatial localization of brain activity related to working memory processing.

Main Methods:

  • Simultaneous collection of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) data during an n-back verbal working memory task.
  • Application of joint independent component analysis (JICA) to model spectral perturbations in EEG oscillations and fMRI activation.
  • Inclusion of multi-channel oscillation features within the JICA model for enhanced analysis.

Main Results:

  • Theta and beta EEG oscillations were modulated by memory load during the early stimulus evaluation stage, correlating with enhanced frontal and parietal lobe activation.
  • Alpha and gamma EEG activity changes, dependent on load, were observed in the late response selection stage, linked to increased activation in frontal, temporal, and parietal areas.
  • Findings indicate that increased working memory load affects both the intensity and timing of EEG activity and recruits specific brain regions differentially across cognitive processing stages.

Conclusions:

  • Simultaneous EEG-fMRI analysis using JICA provides a powerful tool to understand the neural basis of working memory.
  • Working memory load dynamically influences brain activity, affecting both electrophysiological signals and regional brain activation patterns over time.
  • The study highlights the distinct roles of frontal, temporal, and parietal regions in processing varying working memory loads during different phases of cognitive tasks.