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Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents

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Published on: September 10, 2018

Clinical decision analysis in perinatology.

Rohan D'Souza^1,2, Prakesh S Shah^2,3, Beate Sander^2,4

¹Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada.

Acta Obstetricia Et Gynecologica Scandinavica

|November 23, 2017

Summary

Clinical decision-making in perinatology requires specific guidelines for analyzing mother-fetus trade-offs. This study outlines decision analysis methods for evaluating maternal-fetal health outcomes and patient preferences.

Keywords:

Decision analysis model-based economic evaluation obstetrics perinatology pregnancy

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Area of Science:

Perinatal medicine
Decision analysis
Health economics

Background:

Clinical decision-making in perinatology balances maternal and fetal interests.
Existing decision analytic methods lack specific guidelines for the mother-fetus dyad.

Purpose of the Study:

To describe decision analysis basics for perinatology.
To highlight considerations for mother-fetus dyad in clinical and cost-effectiveness analyses.

Main Methods:

Review of decision analysis principles.
Discussion of challenges in perinatal outcome measurement.

Main Results:

Decision analysis requires patient preferences for combined maternal-fetal health states.
Maternal and offspring outcomes over time horizons are crucial.
Quality-adjusted life years present challenges as an outcome measure.

Conclusions:

There is a need for guidelines on decision analysis in perinatology.
Special considerations for the mother-fetus dyad are essential for accurate analyses.