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Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides
Bing-You Yang1, Xue-Yan Bi2, Yan Liu3
1Key Laboratory of Chinese Materia Medica, Ministry of Education of Heilongjiang University of Chinese Medicine, Harbin 150040, China. ybywater@163.com.
Abstract:
Four new compounds, aneglycoside A-C (1-3) and timosaponin U (4), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were determined through extensive spectroscopic analysis, chemical characteristics, and high-resolution mass spectrometry (HRMS). All the isolations were evaluated for cytotoxicity against HepG2, Hela, and SGC7901 human cancer lines. Compounds 1, 2, and 4 showed weak antiproliferative activities on HepG2, Hela, and SGC7901 cells.
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