Pillar[5]arene-Based Supramolecular Organic Framework with Multi-Guest Detection and Recyclable Separation Properties

Area of Science:

• Supramolecular Chemistry
• Materials Science
• Analytical Chemistry

Background:

• Selective detection and separation of target ions/molecules is a significant challenge.
• Supramolecular organic frameworks (SOFs) offer tunable properties for molecular recognition.

Purpose of the Study:

• To construct a novel supramolecular organic framework (SOF-THBP) for selective ion detection and separation.
• To develop metal-ion-coordinated SOFs (MSOFs) for sensing specific anions and amino acids.

Main Methods:

• Synthesis of SOF-THBP using bis-thioacetylhydrazine functionalized pillar[5]arenes.
• Fluorescent sensing of Fe³⁺, Cr³⁺, Hg²⁺, and Cu²⁺ ions using SOF-THBP.
• Recyclable separation of metal ions using SOF-THBP xerogel.
• Construction of MSOFs by coordinating metal ions into SOF-THBP.
• Selective sensing of F⁻, Br⁻, and l-Cys using MSOFs.

Main Results:

• SOF-THBP exhibited fluorescent responses to Fe³⁺, Cr³⁺, Hg²⁺, and Cu²⁺.
• SOF-THBP xerogel achieved >99% absorption rates for recyclable separation of these metal ions.
• Novel MSOFs (MSOF-Fe, MSOF-Hg, MSOF-Cu) were synthesized.
• MSOFs demonstrated selective sensing of F⁻, Br⁻, and l-Cys with detection limits around 10⁻⁸ M.

Conclusions:

• The developed SOF-THBP is effective for selective fluorescent detection and recyclable separation of target metal ions.
• The derived MSOFs provide a versatile platform for sensitive and selective sensing of anions and amino acids.
• This work presents a promising strategy for designing functional supramolecular materials for analytical applications.