Search research articles

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Isolation and profiling of single circulating tumor cells in myeloma: a new workflow for liquid biopsies.

BioTechniques·2026

Same author

Stem-Engineered Aptamers with Enhanced Stability and Affinity for Tumor-Targeted Imaging.

Analytical chemistry·2026

Same author

Breaking the Silence on Genocide in Gaza: Kudos from Jewish Health Professionals.

Canadian journal of occupational therapy. Revue canadienne d'ergotherapie·2026

Same author

Three-Dimensional Organization of Telomeres: An Emerging Prognostic Biomarker in Multiple Myeloma.

Cells·2025

Same author

From genome to gene expression: the genomic landscape of a hybrid species of Eucalyptus urophylla × Eucalyptus grandis and its divergence from parental species hybrid.

BMC plant biology·2025

Same author

A novel oncolytic poxvirus carrying CD47 nanomabs in the treatment of pancreatic cancer by reshaping the immune microenvironment.

Cancer letters·2025

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Feb 18, 2026

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Published on: February 7, 2025

Human milk H₂O₂ content: does it benefit preterm infants?

Monika Cieslak¹, Cristina H F Ferreira², Yulia Shifrin¹

¹Physiology and Experimental Medicine Program, Hospital for Sick Children Research Institute; Department of Paediatrics and Physiology, University of Toronto, Toronto, Ontario, Canada.

Pediatric Research

|November 23, 2017

Summary

This summary is machine-generated.

Human milk

More Related Videos

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

Published on: November 14, 2025

Related Experiment Videos

Last Updated: Feb 18, 2026

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Published on: February 7, 2025

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

Rapid Isolation of Human Breast Milk-Derived Extracellular Vesicles

Published on: November 14, 2025

Area of Science:

Biochemistry
Neonatal Nutrition
Human Milk Composition

Background:

Human milk contains antimicrobial hydrogen peroxide (H2O2).
Preterm infants receive expressed and stored milk, potentially reducing H2O2 benefits.
Understanding H2O2 generation and degradation is crucial for neonatal care.

Purpose of the Study:

To identify factors influencing H2O2 generation in breast milk.
To investigate the stability and degradation pathways of H2O2 in human milk.
To assess the impact of milk handling on H2O2 content for preterm infants.

Main Methods:

Evaluated H2O2 generation/degradation in human and rat milk and mammary tissue.
Assessed the roles of oxytocin and xanthine oxidase in H2O2 production.
Measured H2O2 pH-dependent stability and degradation by lactoperoxidase and catalase.

Main Results:

Xanthine oxidase in breast tissue generates H2O2, stimulated by oxytocin.
Human milk H2O2 stability is greatest in acidic conditions.
H2O2 rapidly degrades at room temperature within 10 minutes, inhibited by lactoperoxidase and catalase.

Conclusions:

Fresh breast milk's H2O2 content is unstable and degrades quickly at room temperature.
Investigating milk handling methods is essential to preserve H2O2 for preterm infants.
Further research is needed to optimize milk storage and feeding practices.