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The pre/parasubiculum: a hippocampal hub for scene-based cognition?
Marshall A Dalton1, Eleanor A Maguire1
1Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.
Current Opinion in Behavioral Sciences
|November 24, 2017
Summary
The pre/parasubiculum, a hippocampal subregion, is crucial for processing spatial scenes, supporting memory, navigation, and future imagination. Its unique neuroanatomy suggests a specialized role in holistic environmental representation.
Area of Science:
- Neuroscience
- Cognitive Science
- Neuroimaging
Background:
- Internal representations of spatially coherent scenes are vital for episodic memory, navigation, and future imagination.
- The hippocampal pre/parasubiculum is consistently activated in human neuroimaging studies of scene-based cognition.
Purpose of the Study:
- To review recent evidence explaining the pre/parasubiculum's engagement in scene-based cognition.
- To explore the neuroanatomical factors contributing to the pre/parasubiculum's role in processing environmental scenes.
Main Methods:
- Review of existing human neuroimaging studies.
- Analysis of the pre/parasubiculum's connectivity and anatomical relationships within the brain.
Main Results:
- The pre/parasubiculum is a primary target of the parieto-medial temporal pathway.
- It integrates foveal and peripheral visual information.
- It is anatomically contiguous with the retrosplenial cortex.
Conclusions:
- These factors suggest the pre/parasubiculum has privileged access to holistic environmental representations.
- The pre/parasubiculum may be neuroanatomically specialized for preferential processing of scenes.
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