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Next-generation Sequencing

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....

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Related Experiment Video

Updated: Feb 18, 2026

Capturing Chromosome Conformation Across Length Scales

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

Corrigendum: The 4D nucleome project.

Job Dekker, Andrew S Belmont, Mitchell Guttman

|November 24, 2017

Summary

This summary is machine-generated.

This article corrects a previously published DOI. The Digital Object Identifier (DOI) ensures proper citation and retrieval of scientific literature.

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High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

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Published on: October 5, 2018

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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Last Updated: Feb 18, 2026

Capturing Chromosome Conformation Across Length Scales

Capturing Chromosome Conformation Across Length Scales

Published on: January 20, 2023

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

High-throughput Identification of Gene Regulatory Sequences Using Next-generation Sequencing of Circular Chromosome Conformation Capture 4C-seq

Published on: October 5, 2018

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

Area of Science:

Bibliometrics
Scholarly Communication

Background:

Accurate citation is crucial for scientific integrity.
Digital Object Identifiers (DOIs) are standard for referencing research.

Purpose of the Study:

To correct an erroneous DOI associated with a published article.
To ensure accurate linking and retrieval of the scientific work.

Main Methods:

Cross-referencing publication records.
Verifying the correct DOI through publisher databases.

Main Results:

The correct DOI for the article has been identified.
The erroneous DOI has been flagged for correction.

Conclusions:

Ensuring accurate DOIs enhances the discoverability and traceability of research.
Correcting citation errors upholds the reliability of scientific records.