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Skin aging parameters: A window to heart block.

Hisham Samir Roshdy1, Mohammad Hassan Soliman1, Ibtesam Ibrahim El-Dosouky1

  • 1Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Clinical Cardiology
|November 24, 2017
PubMed
Summary
This summary is machine-generated.

A high intrinsic skin aging score may indicate a risk for advanced-degree atrioventricular (AV) block. Periodic electrocardiography (ECG) follow-up is recommended for early detection and prevention of sudden cardiac death.

Keywords:
Aging HeartDegenerative Heart BlockSkin Aging ParametersTissue Fibrosis

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Area of Science:

  • Cardiology
  • Dermatology
  • Gerontology

Background:

  • Skin aging can reflect internal health conditions.
  • Intrinsic skin aging parameters were evaluated for their association with heart conditions.

Purpose of the Study:

  • To investigate the relationship between skin aging indicators and the occurrence of advanced-degree atrioventricular (AV) block.
  • To identify potential early markers for heart block.

Main Methods:

  • A cohort of 97 patients was divided into an advanced-degree AV block group (49 patients) and a control group (48 patients).
  • Participants underwent clinical examinations, intrinsic skin aging scoring, and 12-lead surface electrocardiography (ECG).
  • Advanced assessments included echocardiography and coronary angiography when necessary.

Main Results:

  • Patients with AV block showed significantly higher prevalence of uneven pigmentation, fine wrinkles, lax skin, and seborrheic keratosis.
  • Higher intrinsic skin aging scores (especially >6) were strongly correlated with advanced-degree AV block.
  • Seborrheic keratosis emerged as the most potent independent predictor of AV block.

Conclusions:

  • An intrinsic skin aging score exceeding 6 suggests a high risk for developing advanced-degree AV block.
  • Individuals with high skin aging scores warrant regular ECG monitoring for early detection of cardiac conduction abnormalities.
  • Proactive screening can aid in minimizing the risk of sudden cardiac death associated with AV block.