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Local recurrent mammary carcinoma failing multimodality therapy. A solution
P M McCormack1, M S Bains, M E Burt
1Department of Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, New York.
Archives of Surgery (Chicago, Ill. : 1960)
|February 1, 1989
Summary
Surgical resection and reconstruction effectively treat chest wall recurrence after radiation and hormonal therapy for breast cancer. This approach offers palliation and potential cure for advanced, resistant disease.
Area of Science:
- Oncology
- Thoracic Surgery
- Surgical Reconstruction
Background:
- Chest wall recurrence after radiation and hormonal therapy is a rare but debilitating complication.
- Chest wall ulcers secondary to recurrent breast cancer present significant treatment challenges.
Purpose of the Study:
- To evaluate the efficacy of surgical resection and reconstruction for managing chest wall recurrence of mammary carcinoma.
- To assess outcomes in patients with recurrent breast cancer resistant to conventional therapies.
Main Methods:
- Retrospective review of 35 patients treated over 35 years for chest wall recurrence.
- Surgical resection of recurrent tumors followed by reconstruction using mesh or mesh "sandwich" techniques.
- Analysis of patient demographics, recurrence patterns, operative outcomes, and survival rates.
Main Results:
- No operative deaths or need for respiratory support were reported.
- Twenty out of 35 patients survived from 5 to 120 months (median 50 months).
- Surgical intervention was performed for patients with first to fourth recurrences, including one post-mastectomy.
Conclusions:
- Surgical resection and reconstruction represent a viable therapeutic option for chest wall recurrence of mammary carcinoma.
- This surgical approach can provide both palliation and cure for patients with disease resistant to other treatments.